Influenza A Viruses of Human Origin in Swine, Brazil.
Identifieur interne : 000115 ( Main/Exploration ); précédent : 000114; suivant : 000116Influenza A Viruses of Human Origin in Swine, Brazil.
Auteurs : Martha I. Nelson ; Rejane Schaefer ; Danielle Gava ; Maurício Egídio Cantão ; Janice Reis Ciacci-ZanellaSource :
- Emerging infectious diseases [ 1080-6059 ] ; 2015.
Descripteurs français
- KwdFr :
- MESH :
- génétique : Glycoprotéine hémagglutinine du virus influenza, Virus de la grippe A.
- épidémiologie : Brésil, Grippe humaine, Maladies des porcs.
- Animaux, Humains, Phylogenèse, Suidae, Transmission de maladie infectieuse.
- Wicri :
- geographic : Brésil.
English descriptors
- KwdEn :
- MESH :
- chemical , genetics : Hemagglutinin Glycoproteins, Influenza Virus.
- geographic , epidemiology : Brazil.
- epidemiology : Influenza, Human, Swine Diseases.
- genetics : Influenza A virus.
- Animals, Disease Transmission, Infectious, Humans, Phylogeny, Swine.
Abstract
The evolutionary origins of the influenza A(H1N1)pdm09 virus that caused the first outbreak of the 2009 pandemic in Mexico remain unclear, highlighting the lack of swine surveillance in Latin American countries. Although Brazil has one of the largest swine populations in the world, influenza was not thought to be endemic in Brazil's swine until the major outbreaks of influenza A(H1N1)pdm09 in 2009. Through phylogenetic analysis of whole-genome sequences of influenza viruses of the H1N1, H1N2, and H3N2 subtypes collected in swine in Brazil during 2009-2012, we identified multiple previously uncharacterized influenza viruses of human seasonal H1N2 and H3N2 virus origin that have circulated undetected in swine for more than a decade. Viral diversity has further increased in Brazil through reassortment between co-circulating viruses, including A(H1N1)pdm09. The circulation of multiple divergent hemagglutinin lineages challenges the design of effective cross-protective vaccines and highlights the need for additional surveillance.
DOI: 10.3201/eid2108.141891
PubMed: 26196759
PubMed Central: PMC4517702
Affiliations:
Links toward previous steps (curation, corpus...)
Le document en format XML
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Nelson</name></author><author><name sortKey="Schaefer, Rejane" sort="Schaefer, Rejane" uniqKey="Schaefer R" first="Rejane" last="Schaefer">Rejane Schaefer</name></author><author><name sortKey="Gava, Danielle" sort="Gava, Danielle" uniqKey="Gava D" first="Danielle" last="Gava">Danielle Gava</name></author><author><name sortKey="Cantao, Mauricio Egidio" sort="Cantao, Mauricio Egidio" uniqKey="Cantao M" first="Maurício Egídio" last="Cantão">Maurício Egídio Cantão</name></author><author><name sortKey="Ciacci Zanella, Janice Reis" sort="Ciacci Zanella, Janice Reis" uniqKey="Ciacci Zanella J" first="Janice Reis" last="Ciacci-Zanella">Janice Reis Ciacci-Zanella</name></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2015">2015</date><idno type="RBID">pubmed:26196759</idno><idno type="pmid">26196759</idno><idno type="doi">10.3201/eid2108.141891</idno><idno type="pmc">PMC4517702</idno><idno type="wicri:Area/Main/Corpus">000110</idno><idno type="wicri:explorRef" wicri:stream="Main" wicri:step="Corpus" wicri:corpus="PubMed">000110</idno><idno type="wicri:Area/Main/Curation">000110</idno><idno type="wicri:explorRef" wicri:stream="Main" wicri:step="Curation">000110</idno><idno type="wicri:Area/Main/Exploration">000110</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Influenza A Viruses of Human Origin in Swine, Brazil.</title><author><name sortKey="Nelson, Martha I" sort="Nelson, Martha I" uniqKey="Nelson M" first="Martha I" last="Nelson">Martha I. Nelson</name></author><author><name sortKey="Schaefer, Rejane" sort="Schaefer, Rejane" uniqKey="Schaefer R" first="Rejane" last="Schaefer">Rejane Schaefer</name></author><author><name sortKey="Gava, Danielle" sort="Gava, Danielle" uniqKey="Gava D" first="Danielle" last="Gava">Danielle Gava</name></author><author><name sortKey="Cantao, Mauricio Egidio" sort="Cantao, Mauricio Egidio" uniqKey="Cantao M" first="Maurício Egídio" last="Cantão">Maurício Egídio Cantão</name></author><author><name sortKey="Ciacci Zanella, Janice Reis" sort="Ciacci Zanella, Janice Reis" uniqKey="Ciacci Zanella J" first="Janice Reis" last="Ciacci-Zanella">Janice Reis Ciacci-Zanella</name></author></analytic><series><title level="j">Emerging infectious diseases</title><idno type="eISSN">1080-6059</idno><imprint><date when="2015" type="published">2015</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Animals (MeSH)</term><term>Brazil (epidemiology)</term><term>Disease Transmission, Infectious (MeSH)</term><term>Hemagglutinin Glycoproteins, Influenza Virus (genetics)</term><term>Humans (MeSH)</term><term>Influenza A virus (genetics)</term><term>Influenza, Human (epidemiology)</term><term>Phylogeny (MeSH)</term><term>Swine (MeSH)</term><term>Swine Diseases (epidemiology)</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Animaux (MeSH)</term><term>Brésil (épidémiologie)</term><term>Glycoprotéine hémagglutinine du virus influenza (génétique)</term><term>Grippe humaine (épidémiologie)</term><term>Humains (MeSH)</term><term>Maladies des porcs (épidémiologie)</term><term>Phylogenèse (MeSH)</term><term>Suidae (MeSH)</term><term>Transmission de maladie infectieuse (MeSH)</term><term>Virus de la grippe A (génétique)</term></keywords><keywords scheme="MESH" type="chemical" qualifier="genetics" xml:lang="en"><term>Hemagglutinin Glycoproteins, Influenza Virus</term></keywords><keywords scheme="MESH" type="geographic" qualifier="epidemiology" xml:lang="en"><term>Brazil</term></keywords><keywords scheme="MESH" qualifier="epidemiology" xml:lang="en"><term>Influenza, Human</term><term>Swine Diseases</term></keywords><keywords scheme="MESH" qualifier="genetics" xml:lang="en"><term>Influenza A virus</term></keywords><keywords scheme="MESH" qualifier="génétique" xml:lang="fr"><term>Glycoprotéine hémagglutinine du virus influenza</term><term>Virus de la grippe A</term></keywords><keywords scheme="MESH" qualifier="épidémiologie" xml:lang="fr"><term>Brésil</term><term>Grippe humaine</term><term>Maladies des porcs</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Animals</term><term>Disease Transmission, Infectious</term><term>Humans</term><term>Phylogeny</term><term>Swine</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Animaux</term><term>Humains</term><term>Phylogenèse</term><term>Suidae</term><term>Transmission de maladie infectieuse</term></keywords><keywords scheme="Wicri" type="geographic" xml:lang="fr"><term>Brésil</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">The evolutionary origins of the influenza A(H1N1)pdm09 virus that caused the first outbreak of the 2009 pandemic in Mexico remain unclear, highlighting the lack of swine surveillance in Latin American countries. Although Brazil has one of the largest swine populations in the world, influenza was not thought to be endemic in Brazil's swine until the major outbreaks of influenza A(H1N1)pdm09 in 2009. Through phylogenetic analysis of whole-genome sequences of influenza viruses of the H1N1, H1N2, and H3N2 subtypes collected in swine in Brazil during 2009-2012, we identified multiple previously uncharacterized influenza viruses of human seasonal H1N2 and H3N2 virus origin that have circulated undetected in swine for more than a decade. Viral diversity has further increased in Brazil through reassortment between co-circulating viruses, including A(H1N1)pdm09. The circulation of multiple divergent hemagglutinin lineages challenges the design of effective cross-protective vaccines and highlights the need for additional surveillance. </div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">26196759</PMID><DateCompleted><Year>2016</Year><Month>02</Month><Day>22</Day></DateCompleted><DateRevised><Year>2018</Year><Month>11</Month><Day>13</Day></DateRevised><Article PubModel="Print"><Journal><ISSN IssnType="Electronic">1080-6059</ISSN><JournalIssue CitedMedium="Internet"><Volume>21</Volume><Issue>8</Issue><PubDate><Year>2015</Year><Month>Aug</Month></PubDate></JournalIssue><Title>Emerging infectious diseases</Title><ISOAbbreviation>Emerging Infect. Dis.</ISOAbbreviation></Journal><ArticleTitle>Influenza A Viruses of Human Origin in Swine, Brazil.</ArticleTitle><Pagination><MedlinePgn>1339-47</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.3201/eid2108.141891</ELocationID><Abstract><AbstractText>The evolutionary origins of the influenza A(H1N1)pdm09 virus that caused the first outbreak of the 2009 pandemic in Mexico remain unclear, highlighting the lack of swine surveillance in Latin American countries. Although Brazil has one of the largest swine populations in the world, influenza was not thought to be endemic in Brazil's swine until the major outbreaks of influenza A(H1N1)pdm09 in 2009. Through phylogenetic analysis of whole-genome sequences of influenza viruses of the H1N1, H1N2, and H3N2 subtypes collected in swine in Brazil during 2009-2012, we identified multiple previously uncharacterized influenza viruses of human seasonal H1N2 and H3N2 virus origin that have circulated undetected in swine for more than a decade. Viral diversity has further increased in Brazil through reassortment between co-circulating viruses, including A(H1N1)pdm09. The circulation of multiple divergent hemagglutinin lineages challenges the design of effective cross-protective vaccines and highlights the need for additional surveillance. </AbstractText></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Nelson</LastName><ForeName>Martha I</ForeName><Initials>MI</Initials></Author><Author ValidYN="Y"><LastName>Schaefer</LastName><ForeName>Rejane</ForeName><Initials>R</Initials></Author><Author ValidYN="Y"><LastName>Gava</LastName><ForeName>Danielle</ForeName><Initials>D</Initials></Author><Author ValidYN="Y"><LastName>Cantão</LastName><ForeName>Maurício Egídio</ForeName><Initials>ME</Initials></Author><Author ValidYN="Y"><LastName>Ciacci-Zanella</LastName><ForeName>Janice Reis</ForeName><Initials>JR</Initials></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType><PublicationType UI="D013485">Research Support, Non-U.S. Gov't</PublicationType><PublicationType 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Danielle" uniqKey="Gava D" first="Danielle" last="Gava">Danielle Gava</name><name sortKey="Nelson, Martha I" sort="Nelson, Martha I" uniqKey="Nelson M" first="Martha I" last="Nelson">Martha I. Nelson</name><name sortKey="Schaefer, Rejane" sort="Schaefer, Rejane" uniqKey="Schaefer R" first="Rejane" last="Schaefer">Rejane Schaefer</name></noCountry></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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